asthma
Conditions
Interventions
high-FeNO group :no intervention
Xolair-treatment group:no intervention
long-term-follow-up group:no intervention
Sponsors
West China Hospital, Sichuan University
Eligibility
Sex/Gender
All
Age
12 Years to No maximum
Inclusion criteria
Inclusion criteria: Patients diagnosed with asthma in the West China Hospital of Sichuan University(specific standards of diagnosis refers to GINA2018) and age >12 years old.
Exclusion criteria
Exclusion criteria: cannot complete asthma diagnosis related examinations or noncooperation due to other reasons; patients combined with chronic cough and wheezing caused by COPD, tuberculosis, silicosis, fungi, tumors, etc.; patients combined with severe dysfunction in heart, liver, kidney, or severe illness in other systems (such as metabolism, immune, nervous, blood).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Asthma control test;asthma control questionnaire;miniAQLQ;adherence;fractional exhaled nitric oxide (FeNO);nasal nitric oxide (nNO);alveolar nitric oxide;induced sputum examination;lung function;bronchial provocation test;bronchial dilation test;skin prick test;blood routine examination;serum IgE concentration;immune cell cytokines of blood;inflammatory markers of bronchoalveolar lavage fluid and bronchial mucosa;Evaluation of rhinitis symptoms and control;Evaluation of anxiety depressive state; | — |
Contacts
Public ContactChuntao Liu
West China Hospital, Sichuan University
Outcome results
None listed