Research for the treatment of infertility with traditional Chinese medicine

Research for the treatment of infertility with traditional Chinese medicine ‘Zi Gui Nv Zhen capsule’

Status

Recruiting

Phases

Phase 4

Study type

Observational

Source

ChiCTR

Registry ID

ChiCTR1800020269

Enrollment

Unknown

Registered

2018-12-21

Start date

2018-09-20

Completion date

Unknown

Last updated

2019-01-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Infertility

Interventions

Thin endometrium:Zi Gui Nv Zhen capsule

Diminished ovarian reserve:Zi Gui Nv Zhen capsule

Eligibility

Sex/Gender

Female

Age

20 Years to 40 Years

Inclusion criteria

Inclusion criteria: (1) women aged 20-40 who plan to have a pregnancy; (2) meet the diagnostic criteria of endometrium thin; (3) to meet the diagnostic criteria of infertility; (4) the husband's semen examination excludes the male factors (5) anti-mullerian hormone <0.5-1.1ng/mL;Number of antral follicles <7;Follicle stimulating hormone 10 < FSH < 25IU/L at intervals of more than 4 weeks.Any one of the above three items is satisfied; (6) willing to participate in this study and sign the informed consent.

Exclusion criteria

Exclusion criteria: (1) complete removal of bilateral ovaries; (2) currently or within 4 weeks prior to treatment (6 months for long-acting preparations); (3) currently or within 4 weeks prior to group treatment, POI treatment with Chinese medicine or/or other drugs; (4) previous and present history of estrogen-dependent tumors (such as breast cancer and endometrial cancer); (5) previous or current medical history of progesterone dependent tumors (e.g. meningioma); (6) any malignant or precancerous lesion (e.g. endometrial hyperplasia); (7) severe primary diseases, such as cardiovascular, liver, kidney and hematopoietic system, and any liver and kidney dysfunction 2.5 times above normal value; (8) previous or current history of arterial thromboembolism (e.g., angina, myocardial infarction) and/or venous thromboembolism (e.g., deep vein thrombosis, pulmonary embolism); (9) neurological or psychiatric disorders (such as clinical depression) that may interfere with adherence to the study procedures;

Design outcomes

Primary

Measure	Time frame
FSH;LH;AMH;	—

Secondary

Measure	Time frame
ultrasound;	—

Countries

China

Contacts

Public ContactXiangyan Ruan

Beijing Obstetrics and Gynecology Hospital, Capital Medical University

ruanxiangyan@163.com+86 13011215678

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026