EGFR-TKIs-related skin rash
Conditions
Interventions
integrative medicine group:Xiaozhenjiedu formula+Erythromycin Ointment
CHM group:Xiaozhenjiedu formula
Sponsors
Oncology Department, Guangdong Provincial Hospital of Chinese Medicine
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Diagnosed with non-same cell lung cancer by pathology and has been receiving EGFR-TKIs treatment; 2. Had the skin rash related EGFR-TKIs; 3. Aged 18 years or older; 4. Estimated survival time more than 3 months; 5. Normal function of bone marrow, liver, kidney, heart and lung; 6. Can understand the study well and sign the written informed consent.
Exclusion criteria
Exclusion criteria: 1. The skin of the affected area is damaged; 2. Combine with other tumors; 3. Combine with active tuberculosis and other serious infectious diseases; 4. Have received chemotherapy, radiotherapy, other targeted therapy or immunopreparations within the last two months; 5. Received orally Chinese herbal medicine or Chinese patent medicine with a function of clearing heat and resolving toxins, such as jinyinhua ???, kushen ??, in the course of trial; 6. Have serious brain or mental illness, or have no legal capacity to prosecute, medical or ethical reasons affect the continuation of the study; 7. Have the history of organ transplantation (including autologous bone marrow transplantation and peripheral stem cell transplantation); 8. Pregnant or lactating women.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Papulopustular rash; | — |
Secondary
| Measure | Time frame |
|---|---|
| FACT-L, KPS;Adverse events;Response Rate; | — |
Countries
China
Contacts
Public ContactYihong Liu
Guangdong Provincial Hospital of Chinese Medicine
Outcome results
None listed