Sepsis-induced myopathy
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: (1) Aged 18 to 85 years old; (2) Meet the 3.0 standard of sepsis, it is diagnosed as sepsis (infection + qSOFA score = 2 points); (3) First admission to ICU; (4) MRC-SS 7 days; (6) Survival in the ICU is expected.
Exclusion criteria
Exclusion criteria: (1) A confirmed pregnancy or urine pregnancy test is positive; (2) Patients who have been amputated; (3) A newly diagnosed primary neuromuscular disease when admitted to the hospital; (4) Patients with metastatic tumors.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| cross-sectional area of the Rectus Femoris;Incidence of Time to Event; | — |
Secondary
| Measure | Time frame |
|---|---|
| expression levels of serum myostatin;MRC-SS score;the motor function scores in the Functional Independence Rating Scale;ealth-related quality of life score;ICU miantain days;days of hospital stay;duration of invasive/non-invasive mechanical ventilation;case of re-entered the ICU;times of re-entered the ICU;case of re-admission of hospital;times of re-admission of hospital; | — |
Countries
China
Contacts
The First Affiliated Hospital of Guangzhou University of Chinese Medicine