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Single-center comparison for the efficacy and safety of posterior cervical single-door open laminoplasty with mini-titanium plate fixation and posterior cervical double-door open laminoplasty with lateral mass screw fixation and fusion in the treatment of Ossification of Posterior Longitudinal Ligament ( OPLL )

Single-center comparison for the efficacy and safety of posterior cervical single-door open laminoplasty with mini-titanium plate fixation and posterior cervical double-door open laminoplasty with lateral mass screw fixation and fusion in the treatment of Ossification of Posterior Longitudinal Ligament ( OPLL )

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR1800020231
Enrollment
Unknown
Registered
2018-12-20
Start date
2017-12-01
Completion date
Unknown
Last updated
2019-01-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Ossification of Posterior Longitudinal Ligament ( OPLL )

Interventions

A:Posterior cervical single-door open laminoplasty with mini-titanium plate fixation
B:Posterior cervical double-door open laminoplasty with lateral mass screw fixation and fusion

Sponsors

Shandong provincial hospital affiliated to Shandong university
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1) patients aged 18-65 years, without gender limitation, are willing to sign informed consent; 2) patients diagnosed with OPLL,CT showed that the compression of the posterior longitudinal ligament ossification involve more than 3 spinal segments; 3) patients presented with limbs numbness, walking instability, or other spinal cord, nerve root compression symptoms, which may be associated with OPLL; 4)Conservative treatment is invalid.

Exclusion criteria

Exclusion criteria: 1) Cervical ligamentous ossification, cervical trauma, cervical cancer, cervical tuberculosis and other inflammatory diseases; 2) accompanied by other spine parts of the disease affect the clinical symptoms of patients; 3) associated with amyotrophic lateral sclerosis and other motor neuron diseases and other neurological diseases; 4) poor health condition, unable to tolerate surgery; 5) patients (or their guardians) can not give full informed consent for adult dysfunction; 6) patients who have participated in other clinical trials in the past 1 month; 7) patients with active hepatitis B (including HBeAg) or serological markers (HBsAg or / and HBeAg or / and HBcAb), hepatitis C, tuberculosis, cytomegalovirus infection, severe fungal infection, HIV infection or patients with Turmor.

Design outcomes

Primary

MeasureTime frame
JOA scale;Ossification progress;—

Secondary

MeasureTime frame
Neck disability index;visual analogue scale;curvature index;Incidence rate of C5 root palsy;C2-C7 SVA;—

Countries

China

Contacts

Public ContactShijie Han

Shandong provincial hospital affiliated to Shandong university

86774570@qq.com+86 18678787086

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026