gastroesophageal reflux-induced chronic cough
Conditions
Interventions
Index test:Pepsin 
in 
of 
Sponsors
Shanghai Tongji Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Aged 18 to 80 years old; 2. Cough duration>8weeks; 3. Pulmonary function test: FEV1/FVC=70%, FEV1>80% of the expected value; 4. To be able to understand and correctly complete the above scoring table.
Exclusion criteria
Exclusion criteria: 1. Pregnancy and lactation women; 2. Smoking or smoking less than two years; 3. Reading writing disabilities; 4. Prior to the doctor for cough etiology of treatment,and symptom improvement; 5. fever, hemoptysis, wheezing, etc; rales in the lungs, General treatment including antibiotics treatment ineffective; The chest radiograph showed abnormalities.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Pepsin in sputum;MII-pH;capsaicine cough threshold;Cough symptom score;lung function test +bronchial provocation test;induced sputum;Pepsin in exosome of sputum; | — |
Countries
China
Contacts
Public ContactXianghuai Xu
Shanghai Tongji Hospital
Outcome results
None listed