Glaucoma
Conditions
Interventions
Case series:Different treatment methods
Sponsors
The Eye Hospital, School of Ophthalmology and Optometry, Wenzhou Medical University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Aged 18 or above; 2. Acute primary angle closure patients diagnosed by glaucoma specialties: (1) presence of at least 180 degree of the posterior pigmented trabecular meshwork not visible on gonioscopy in the primary position of gaze without indentation in the affected eye; (2) raised IOP of at least 21 mmHg; (3) presence of at least 2 of the following symptoms: acute blurred vision, ocular pain, headache, nausea and vomitting; (3) presence of at lest 3 of the following signs: conjunctival injection, corneal epithelial edema, mid-dilated unreacitve pupil and/or a shallow anterior chamber; 3. Primary angle-closure glaucoma diagnosed by glaucoma specialties: (1) presence of at least 180 degree of the posterior pigmented trabecular meshwork not visible on gonioscopy in the primary position of gaze without indentation; (2) existence of glaucomatous optic neuropathy defined as neuroretinal rim loss with a vertical cup-to-disc ratio of greater than 0.7 or between eye vertical cup-to-disc ratio asymmetry of greater than 0.2; (3) a VF defect suggestive of glaucoma: the glaucoma hemifield test graded outside normal limits; a cluster of three contiguous points at the 5% level on the pattern deviation plot; Pattern standard deviation<0.05 in healthy poputlation. 4. informed consent obtained from the patient or their agent.
Exclusion criteria
Exclusion criteria: Patients with any of the following conditions: 1. ocular conditions effecting the intraocular pressure test; 2. corrected visual acuity worse than 0.5 logMAR, or other conditions reulting in disability to perform reliable visual field tests (reliable visual field tests defined as fixation losses < 20%, false-positive and false-negative rates of less than 15%) or OCT results (signal strength=6); 3. other cular conditions resulting in change of fundus and visual field results.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Best corrected visual acuity;intraocular pressure;visual field index;vertical cup to disc ration;central anterior chamber depth; | — |
Secondary
| Measure | Time frame |
|---|---|
| mean deviation; | — |
Contacts
Public ContactLiang Yuanbo
The Eye Hospital, School of Ophthalmology and Optometry, Wenzhou Medical University
Outcome results
None listed