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Effect of pretreatment with Levonorgestrel-Releasing Intrauterine System on FET outcomes in Women with Adenomyosis

Effect of pretreatment with Levonorgestrel-Releasing Intrauterine System on FET outcomes in Women with Adenomyosis

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR1800020172
Enrollment
Unknown
Registered
2018-12-19
Start date
2018-12-06
Completion date
Unknown
Last updated
2019-01-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

adenomyosis

Interventions

Sponsors

Shanghai Ninth Hospital
Lead Sponsor

Eligibility

Sex/Gender
Female

Inclusion criteria

Inclusion criteria: Patients were diagnosed using both the transvaginal ultrasound study (TVS)and magnetic resonance image(MRI) criteria. The main criteria for the sonographicand MRI diagnosis of adenomyosis will be: (1) the appearance of asymmetrical thickeningof the myometrium, irregular cystic areas within the myometrium, and linear striations radiating out from the myometrium; (2) =42 years old at the time of commencing frozen-thawed embryo transfer (FET); (3) undergoing FET for the first cycle; (4) the present of at least one good cryopreserved day 3 embryo.

Exclusion criteria

Exclusion criteria: (1) transfer of a poor quality embryo (grades 3 or 4); (2) a history of myomectomy; (3) a pelvic ultrasound that showed the presence of uterine fibroids, a hydrosalpinx, or endometrial polyps (all known causes of implantation failure).

Design outcomes

Primary

MeasureTime frame
implantation rate;

Secondary

MeasureTime frame
Live birth rate;

Countries

China

Contacts

Public ContactYun Wang

Shanghai Ninth People's Hospital, Shanghai Jiaotong University School of Medicine

wangy1860@sh9hospital.org+86 021 23271699-5538

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026