septic shock
Conditions
Interventions
UGDT group:Patients were performed cardiopulmonary and renal ultrasonography to guide fluid resuscitation and the use of inotropic drugs in 0h, 6h, 12h and 24h after enrollment
GDT group: fluid resuscitation will be guided by routine index such as CVP, MAP, ScvO2
Sponsors
Department of Critical Care Medicine, Affiliated Hospital of Zunyi Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: (1) Infection or suspected infection; (2) Sepsis and the need for vasopressor therapy to maintain average arterial pressure(MAP) = 65 mmmHg and lactate concentration to > 2mmol/L after adequate fluid resuscitation; (3) Aged 18 to 80 years old; (4) Length of stay in ICU = 24 hours; (5) Initial diagnosis of septic shock; (6) Informed consent to participate in the study.
Exclusion criteria
Exclusion criteria: (1) The patients or his family members don't agree to participate in the study or sign informed documents; (2) Patients with acute coronary syndrome, fluid overload, heart failure and history of COPD; (3) Patients with septic shock re-enter ICU due to the same cause; (4) Length of stay in ICU for less than 24 hours; (5) Pregnant status.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| clearance rate of lactate; | — |
Contacts
Public ContactChen Ni
Department of Critical Care Medicine, Affiliated Hospital of Zunyi Medical University
Outcome results
None listed