Spinocerebellar ataxia type 3
Conditions
Interventions
1:Sham stimulate
Sponsors
First Affiliated Hospital, Fujian Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Patients with detectable clinical signs and confirmed genetic diagnosis with SCA3; 2. SCA3 patients aged 20 - 80 years; 3. Patients or their family members have informed consent to the study and signed relevant documents.
Exclusion criteria
Exclusion criteria: 1. Patients who have concomitant epilepsy; 2. History of seizure or heat convulsion; 3. Patients on neuroleptics; 4. Patients with dementia (MMSE<25) or any unstable medical disorder; 5. History or current unstable hypertension; 6. History of head injury or neurosurgical interventions; 7. History of any metal in the head (outside the mouth); 8. Known history of any metallic particles in the eye, implanted cardiac pacemaker, implanted neurostimulators, surgical clips (above the shoulder line) or any medical pumps; 9. History of frequent or severe headaches; 10. History of migraine; 11. History of hearing loss; 12. History of cochlear implants; 13. History of drug abuse or alcoholism; 14. Pregnancy or not using a reliable method of birth control; 15. Participation in current clinical study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| International Cooperative Ataxia Rating Scale (ICARS); | — |
Countries
China
Contacts
Public ContactShi-Rui Gan
First Affiliated Hospital, Fujian Medical University
Outcome results
None listed