Diarrhoea-Predominant Irritable Bowel Syndrome
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Adult patients aged 18–60 years suffer from IBS-D as defined by Rome III criteria and IBS-D was caused by spleenqi deficiency according to the diagnostic methods of the Chinese medicine. At the end of the screen period, IBS-D patients were recruited in to treament group if they exhibited diarrhea the occurred for at least 2 days/week and sign the informed consent form. Furthemore, the recruiters did not participate in other clinical trials.
Exclusion criteria
Exclusion criteria: Patients excluded from study participation had the following: aged under 18 or over 60; stool with pus and blood or with mucus; females who were pregnant or nursing; previous gastrointestinal or abdominal surgery; presence of primary disease such as cardiovascular disease, kidney disease, or hematopoietic system disease; diagnosis of any psychiatric disease; recent excessive consumption of alcohol, or involvement in any investigational medications during the 2 weeks prior to screening. Patients who were allergic to the drugs used in the trial were also excluded.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| microRNA;gastrointestinal symptom rating Scale; | — |
Countries
China
Contacts
Shandong University of Traditional Chinese Medicine