panic disorder
Conditions
Interventions
Group 2:Cognitive Behavior Therapy Combined with True Stimulation of TMS
Group 1:Cognitive behavioral therapy combined with TMS pseudostimulus
normal control group (not randomized):non
Sponsors
Beijing Anding Hospital, Capital Medical University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1.Panic disorder patients, 50 cases, in our hospital outpatient patients. (1) Panic disorder patients who meet DSM-IV diagnostic criteria; (2) The severity of panic disorder scale scored more than 7 points; (3) Age 18-45 years old; (4) Junior high school education level above; (5) No drug treatment was given within 4 weeks; (6) Sign informed consent. 2. Normal controls, 25 healthy volunteers from the community: (1) Aged 18-45 years old, right-handed, junior high school education or above; (2) No major physical diseases or psychiatric diseases that meet the diagnostic criteria; (3) No history of mental disorders, no family history of mental disorders; (4) It does not meet the diagnostic criteria of DSM-IV axis II personality disorder; (5) It matched OCD group in gender, age, handedness and educational background; (6) Sign informed consent.
Exclusion criteria
Exclusion criteria: 1. According to the judgement of researchers, patients are at risk of suicide or injury to others; 2. History of brain organic diseases and major somatic diseases; 3. Conformity with other mental disorders such as schizophrenia and bipolar affective disorder; 4. Evidence of drug dependence and use of psychoactive substances; 5. Patients who have received electroconvulsive, transcranial magnetic stimulation, deep brain stimulation and other treatments affecting brain function in the past; 6. Those who have metal implants and dentures in vivo are in pregnancy and lactation, and have claustrophobia and other persons who can not be scanned by MRI.
Design outcomes
Secondary
| Measure | Time frame |
|---|---|
| Clinical global impression, CGI;SCL-90;Personal and Social Performance Scale, PSP;VAS; | — |
Primary
| Measure | Time frame |
|---|---|
| Panic Disorder Severity Scale;Hamilton Depression Rating Scale;Hamilton Anxiety Scale, HAMA; | — |
Countries
China
Contacts
Public ContactYang Xiangyun
Beijing Anding Hospital, Capital Medical University
Outcome results
None listed