Chemotherapy-induced alopecia
Conditions
Interventions
Group 1:YH0618 granule
Group 2:Placebo granule
Sponsors
Guangdong Provincial Hospital of Chinese Medicine
Eligibility
Sex/Gender
Female
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: (1) females with breast cancer aged between 18-75 years; (2) will receive first chemotherapy; (3) scheduled to receive chemotherapeutic agents containing taxanes or anthracyclines; (4) chemotherapy regimen will last at least 6 cycles and every three weeks is a cycle; (5) adverse events assessed using WHO toxicity classification criteria< II grade; (6) a life expectancy is at least 6 months.
Exclusion criteria
Exclusion criteria: (1) subjects with a medical history of hair transplantation; (2) suffer from psoriasis or severe scalp infection; (3) hair loss induced by alopecia areata, alopecia totalis or scalp injury, etc.; (4) pregnancy, lactation or potential pregnancy; (5) allergic to some specific food, like black soybean, etc.; (6) severe cardiac, hepatic, renal, pulmonary and hematic lesions or other diseases which will affect their survival; (7) who have any severe mental or behavioral disorders that cannot be fully informed; (8) be suspected or do have a history of alcohol and drug abuse, or cannot cooperate with the treatment process; (9) cannot understand or fill in questionnaires because of cognitive disorders or low level of literacy; (10) a variety of factors affecting drug taking and absorption, such as inability to swallow, chronic diarrhea, intestinal obstruction, etc.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Indexes of hair loss; | — |
Secondary
| Measure | Time frame |
|---|---|
| Assessment of quality of life;blood routine examination;Assessment of hepatic and renal function; | — |
Countries
China
Contacts
Public ContactCHEN Jianping
School of Chinese Medicine, The University of Hong Kong
Outcome results
None listed