Diaper dermatitis
Conditions
Interventions
Group 1:Compound Lithospermum oil
Group 2:ointment of zink oxide
Sponsors
Beijing Children's Hospital Affiliated to Capital Medical University
Eligibility
Sex/Gender
All
Age
No minimum to 1 Years
Inclusion criteria
Inclusion criteria: 1. To meet the diagnostic criteria of Western medicine for diaper dermatitis: The skin of diaper area is stimulated by urine, feces and repeated rubbing; Limited dermatitis in diaper area; 2. The severity of diaper dermatitis was mild or moderate; 3. aged < 12 months male and female; 4. The legal guardian of the subject can fully understand the purpose of the test, and voluntarily to participate in the clinical trial and sign the consent form.
Exclusion criteria
Exclusion criteria: 1) The subjects who used the similar products, oral antihistamines, antibiotics or other anti-inflammatory drugs, glucocorticoids and other external drugs on the lesion area one week before the study. 2) Skin lesion combined virus and fungal infection; 3) There are other skin diseases (such as atopic dermatitis, enteropathic acrodermatitis, etc.) besides the diaper area, which obviously affect the evaluation of the children with skin diseases; 4) Premature infants and malnourished children; 5) The children with severe primary diseases such as cardiovascular, cerebrovascular, liver, kidney, endocrine, immune, hematopoietic system and psychiatric diseases 6) Allergic to research drug ingredients; 7) Patients who are participating in or have participated in other clinical trials within 3 months; 8) Researchers think it is not suitable for the candidates.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The overall improvement rate of skin lesions; | — |
Secondary
| Measure | Time frame |
|---|---|
| The effective rate of skin lesions;The clinical cure rate of skin lesions;The clinical healing time of skin lesions;the difference of mean values of non-invasive skin parameters (TEWL, Cor, PH) at the lesion site;The difference of the total score of the Dermatitis Family Impact Questionnaire (DFI); | — |
Countries
China
Contacts
Public ContactLin Ma
Beijing Children's Hospital Affiliated to Capital Medical University
Outcome results
None listed