Chronic rhinosinusitis
Conditions
Interventions
Group 1:Pump remifentanil 0.5ug/kg (1min) 0.05ug/kg/min after surgery
Group 2:Pump remifentanil 0.5ug/kg (1min) 0.05ug/kg/min and dexmedetomidine 1ug/kg(10min)+0.5ug/kg/h after surgery
Group 3:Pump remifentanil 0.5ug/kg (1min) 0.05ug/kg/min and dexmedetomidine 1ug/kg(10min)+0.5ug/kg/h before induction
Sponsors
Department of Anesthesiology, The Third Affiliated Hospital, Sun Yat-Sen University, Guangzhou, Guangdong Province
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: 1. Diagnosed as chronic sinusitis, chronic sinusitis with nasal polyps, chronic sinusitis with nasal septum deviation; 2. Patients voluntarily participated and signed informed consent; 3. Aged between 18 and 60 years; 4. To perform elective endoscopic sinus surgery; 5. ASA I-II.
Exclusion criteria
Exclusion criteria: 1. the patients refused to participate in this study; 2. with myocardial ischemia; 3. with sinus bradycardia, sinus syndrome; 4. with bronchial asthma; 5. with a history of neurological and mental illness, who took monoamine oxidase inhibitors; 6. those who are known to be allergic to remifentanil or dexmetomidine; 7. others
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| MAP; | — |
Countries
China
Contacts
Public ContactPinjie Huang
Department of Anesthesiology, The Third Affiliated Hospital, Sun Yat-Sen University, Guangzhou, Guangdong Province
Outcome results
None listed