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Synergistic mechanism of hyperhomocysteinemia with poor efficacy

Synergistic mechanism of hyperhomocysteinemia with poor efficacy

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR1800020048
Enrollment
Unknown
Registered
2018-12-12
Start date
2018-12-10
Completion date
Unknown
Last updated
2018-12-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

hyperhomocysteinemia

Interventions

Case series:B treatment + VB2 + betaine

Sponsors

China Rehabilitation Research Center, Beijing Boai Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: Patients in the ward and outpatient Hhcy can take regular medication and collect blood according to the time point, without severe liver and kidney dysfunction, and sign informed consent. Sequential enrollment in Hhcy patients, fill in CRF, determine baseline HCY / folic acid / VB12 / liver and kidney function; folic acid, vitamin B6, mecobalamin after routine treatment for 1 month, review Hcy levels, screening out less than 20% or not normal Value (60 cases). They were randomly divided into the conventional treatment group and the combination treatment group.

Exclusion criteria

Exclusion criteria: Patients who had been treated for HCY in the external hospital were not included in the study group.

Design outcomes

Secondary

MeasureTime frame
Methionine synthase;Cystathionine B synthetase;

Primary

MeasureTime frame
Folic acid;Methylenetetrahydrofolate reductase;vitamin B12;

Countries

China

Contacts

Public ContactDu Xiao-Xia

China Rehabilitation Research Center Beijing Boai Hospital

364906784@qq.com+86 19910619000

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 18, 2026