primary hepatocellular carcinoma with cirrhosis background
Conditions
Interventions
A:TACE adjuvant therapy was performed 2 weeks before surgery, and intraoperative indocyanine green fluorescence imaging negative imaging hepatocellular carcinoma resection was performed
B:Intraoperative indocyanine green fluorescence imaging hepatectomy was performed
Sponsors
Institute of Automation, Chinese Academy of Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: (1) Primary liver cancer was diagnosed as BCLC B/C stage (PVTT type I-III) or IIb-IIIa stage (2017 version of primary liver cancer diagnosis and treatment specifications) according to pathological diagnostic norms or clinical diagnostic criteria; (2) Cirrhosis with child-pugh A/B liver function; (3) Aged 18 to 75 years old male and female; (4) score of general physical condition ECOG: 0-2;No major organ dysfunction; (5) Able to obtain complete follow-up information, understand the status of this study and sign an informed consent form.
Exclusion criteria
Exclusion criteria: (1) The coagulation function is seriously decreased and cannot be corrected; (2) The main portal vein was completely embolized by cancer thrombus, with less collateral vessel formation; (3) Patients with active hepatitis or severe infection who cannot be treated at the same time; (4) There was a significant decrease in WBC and platelet in peripheral blood, with WBC 2mg/dl or creatinine clearance rate < 30ml/min; (6) Dysplasmic fluid or multiple organ failure; (7) Allergic to indocyanine green, doxorubicin, LPT and iodized oil; (8) The researcher believes that the subject may not be able to complete the study or comply with the requirements of the study (for management reasons or other reasons).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Overall survival rate; | — |
Secondary
| Measure | Time frame |
|---|---|
| Disease-free survival rate;Tumor detection rate and R0 resection rate;Liver insufficiency rate;Adverse event rate; | — |
Countries
China
Contacts
Public ContactKun Wang
Institute of Automation, Chinese Academy of Sciences
Outcome results
None listed