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Hemodynamic variations in patients with intracranial aneurysms and hypertension before and after antihypertensive medication based on 4D flow MRI, DCE MRI and ASL MRI (Honest-MRI)

Hemodynamic variations in patients with intracranial aneurysms and hypertension before and after antihypertensive medication based on 4D flow MRI, DCE MRI and ASL MRI (Honest-MRI)

Status
Recruiting
Phases
Early Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR1800019985
Enrollment
Unknown
Registered
2018-12-11
Start date
2018-12-30
Completion date
Unknown
Last updated
2021-01-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

intracranial aneurysm

Interventions

Short-term anti-hypertensive medication group:Take antihypertensive drugs in a short period of time (within 1 day)
Long-term anti-hypertensive medicationgroup:Long-term use of antihypertensive drugs.

Sponsors

Beijing Tiantan Hospital, Capital Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 75 Years

Inclusion criteria

Inclusion criteria: 1. Patients with unruptured intracranial aneurysms and hypertension; 2. Three-dimensional angiographic data of patients are complete, and the image quality meets the requirements of dynamic simulation; 3. The size of the aneurysm is greater than or equal to 4 mm; 4. Ages greater than or equal to 18 years old, less than or equal to 75 years old.

Exclusion criteria

Exclusion criteria: Aneurysms associated with arteriovenous malformations or dural arteriovenous fistula, dissection aneurysms, fusiform aneurysms, and blood-blisyter like aneurysms, and aneurysms less than 4mm in size.

Design outcomes

Primary

MeasureTime frame
flow velocity in the aneurysm;wall shear stress;streamline;vortex;Flow velocity in the parent artery.;flow volume in the aneurysm;Flow volume in the parent artery.;Oscillating shear index;Oscillating shear index;Ktrans;aneurysm size;aneurysm height;aneurysm neck size;Inflow angle;

Countries

China

Contacts

Public ContactAihua Liu

Beijing Tiantan Hospital, Capital Medical University

liuaihuadoctor@163.com+86 15901398688

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026