Mild cognitive impairment
Conditions
Interventions
Group 1:Tai Chi + health education
Group 2:Aerobic exercise + health education
Group 3:Health education
Sponsors
Fujian University of Traditional Chinese Medicine
Eligibility
Sex/Gender
All
Age
50 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. Match the diagnostic criteria of MCI; 2. MoCA score: 18-25; 3. Aged between 50 and 75 years; 4. No regular physical exercise for at least half a year (exercise with a frequency of at least twice a week and 20 minutes per session); 5. right handedness; 6. Informed consent and voluntary participation.
Exclusion criteria
Exclusion criteria: 1. Hypertensive patients with uncontrollable blood pressure; 2. A history of alcohol and drug abuse; 3. Cognitive impairment was caused by other diseases (such as depression, drugs, poisoning, cerebrovascular diseases); 4. Patients with a history of mental illness, or with severe aphasia and audio-visual impairment, or with severe organ failure, history of myocardial infarction, history of coronary heart disease, musculoskeletal system disease, contraindications of exercise, color blindness and low educational level who cannot finish the test; 5. MRI contraindications such as dentures, porcelain teeth, pacemakers; or taking opioids, benzodiazepines and other drugs which affect the brain imaging; 6. Participating in other study subjects that influence the results of this study. Those who meet any of the above criteria will not be included in the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Montreal cognitive function assessment scale; | — |
Secondary
| Measure | Time frame |
|---|---|
| Wechsler adult memory scale (China Revised);Test of Attentional Performance (TAP) 2.3;Stroop color word card test;MRI and functional MRI; | — |
Countries
China
Contacts
Public ContactJiao Liu
Fujian University of Traditional Chinese Medicine
Outcome results
None listed