Pregnancy and parturition
Conditions
Interventions
A:Intravenous injection 7.5 ug/kg before epidural anesthesia
B:Intravenous injection 5 ug/kg before epidural anesthesia
C:Intravenous injection 2.5 ug/kg before epidural anesthesia
D:given equal volume of saline(5 ml)
Sponsors
The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University
Eligibility
Sex/Gender
Female
Age
18 Years to 35 Years
Inclusion criteria
Inclusion criteria: 1. Aged 18~35 years; 2. ASA I~II; 3. Parturients planned for elective cesarean sections under epidural anesthesia; 4. At 37 to 42 weeks of gestation, B-ultrasonography showed intrauterine single live fetus, no intrauterine distress, umbilical cord around the neck, congenital malformation and other abnormal conditions.
Exclusion criteria
Exclusion criteria: 1. History of liver and kidney dysfunction and cardiopulmonary diseases; 2. History of allergy; 3. Parturients with mental and neurological diseases; 4. Parturients who are not suitable for epidural anesthesia; 5. Pregnancy women who are complicated with hypertension, eclampsia and other diseases; 6. Abnormal function of placenta abruption, placenta previa and coagulation. 7. Parturients with history of drug and alcohol abuse,
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The incidence and intensity of shivering; | — |
Secondary
| Measure | Time frame |
|---|---|
| Pulse oxygen saturation;Blood pressure;Heart rate;Respiratory rate;OAA/S score;Apgar score of neonates;Analysis of blood gas of umbilical cord;Adverse events;body temperature;level of epidural block;time from epidural anesthesia to incision;time from epidural anesthesia to wound dressing;amount of fluid given intraoperatively;total estimated blood loss; | — |
Countries
China
Contacts
Public ContactMingpin Hu
The Second Affiliated Hospital & Yuying Children's Hospital of Wenzhou Medical University
Outcome results
None listed