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The Research for the morphylogy, function and lipids of meibomian glands in diabetic patients with dry eye

The Research for the morphylogy, function and lipids of meibomian glands in diabetic patients with dry eye

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR1800019939
Enrollment
Unknown
Registered
2018-12-09
Start date
2019-01-01
Completion date
Unknown
Last updated
2018-12-10

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

dry eye disease

Interventions

normal group:none
normal dry eye group:none
diabetic group without dry eye:none
diabetic group with dry eye:none

Sponsors

Ophthalmology department,Yangpu Hospital Affiliated to Tongji University
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. At least 40 years old; 2. All assessments that qualify in right eye; 3. Patients with type 2 diabetes fulfilled the criteria established by the WHO in 2014; 4. Patients with dry eye met the criteria set by the TFO DEWS II in 2017; 5. Willingness to comply with study protocol.

Exclusion criteria

Exclusion criteria: 1. Active eye inflammation and infection within past 3 months; 2. Use of any eye drops; 3. Wearing contact lens within past 3 months; 4. Ocular laser surgery or other surgery and ocular trauma within past 3 months; 5. Systemic disease condition that causes dry eye; 6. Autommiune disease and desmosis.

Design outcomes

Primary

MeasureTime frame
Ocular Surface Disease Index Questionair;noninvasive tear breakup time;Schirmer's test without anesthesia;fluorescein staining of the cornea;loss of meibomian gland;assessment of eye lid margin;meibomian gland acinar longest diameter;meibomian gland acinar shortestdiameter;meibomian gland acinar unit density;meibomian gland acinar unit area;

Countries

China

Contacts

Public ContactQin Yang

Ophthalmology department, Yangpu Hospital Affiliated to Tongji University

yangqin33@sina.com+86 13585748664

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 12, 2026