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Effect and central mechanism of acupuncture for constipation-type irritable bowel syndrome based on functional magnetic resonance imaging

Exploring the brain network mechanism of acupuncture treatment for irritable bowel syndrome from the brain-intestinal axis based on functional magnetic resonance imaging

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR1800019927
Enrollment
Unknown
Registered
2018-12-09
Start date
2019-01-01
Completion date
Unknown
Last updated
2018-12-10

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Constipation-predominant irritable bowel syndrome

Interventions

acupuncture group:ture acupuncture
sham acupuncture group:sham acupuncture

Sponsors

The second affiliated hospital of Guiyang College of Traditional Chinese Medicine
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: (1) According to the western diagnostic criteria of constipation-type irritable bowel syndrome, and excluding intestinal organic diseases by colonoscopy; (2) Patients between the ages of 18 and 65, male or female; (3) Volunteer for this study and sign the informed consent form. PS: Patients who meet the above three items could be included in this study.

Exclusion criteria

Exclusion criteria: (1) Does not meet the above Western diagnostic criteria and inclusion criteria,people who were Pregnant or lactating , and possess an allergic constitution; (2) Patients with severe heart, kidney, liver, brain, tumor and blood system disease; (3) Patients with severe mental disorders and those taking anti-anxiety and anti-depression drugs; (4) patients who have a history of fainting during acupuncture; (5) patients who had been treated with drugs affecting gastrointestinal function within 2 weeks; (6) patient are participating in other clinical trials. PS: Patients who meet any of the above criteria shall be excluded.

Design outcomes

Primary

MeasureTime frame
cleveland clinic score;functional magenetic resonance imaging;

Secondary

MeasureTime frame
Self-rating Anxiety Scale;Self-rating Depression Scale;Neuropeptide Y;diamine oxidase;D-lactic acid;

Countries

China

Contacts

Public ContactLingmin Jin

Guiyang College of Traditional Chinese Medicine

king-jlm@163.com+86 18886087313

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026