Injection pain associated with rocuronium
Conditions
Interventions
Control Group:Local warming temperature 32 degrees centigrade combined with intravenous preinjection of 2ml saline
Local warming Group:Local warming temperature 43 degrees centigrade combined with intravenous preinjection of 2ml saline
Lidocaine Group:Local warming temperature 32 degrees centigrade combined with intravenous preinjection of 2ml lidocaine
Local warming combined with lidocaine Group:Local warming temperature 43 degrees centigrade combined with intravenous preinjection of 2ml lidocaine
Sponsors
West China Hospital, Sichuan University
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. Patients with general anesthesia surgery; 2. ASA classification I-III ; 3. Patients aged 18-65 who signed the informed consent.
Exclusion criteria
Exclusion criteria: 1. Communication barriers; 2. Difficult airway can be expected; 3. Allergy to general anesthesia drugs, history of malignant hyperthermia or family history; 4. Preoperative administration of drugs affecting neuromuscular conduction function (such as aminoglycoside antibiotics, anti-convulsion, cortisol hormones, etc.);
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of rocuronium injection pain related limb withdrawal in four groups; | — |
Secondary
| Measure | Time frame |
|---|---|
| Incidence of moderate and severe rocuronium injection pain-related limb withdrawal in four groups;Rocuronium injection pain induced heart rate changes in four groups;Rocuronium injection pain induced changes in blood pressure in four groups;Adverse events occurred during rocuronium injection in four groups;Scores of endotracheal intubation conditions in four groups; | — |
Countries
China
Contacts
Public ContactQian Li
West China Hospital, Sichuan University
Outcome results
None listed