Idiopathic Membranous Nephropathy
Conditions
Interventions
PLA2R???:Cyclophosphamide combined with hormone therapy
PLA2R positive Group:Cyclophosphamide combined with hormone therapy
Sponsors
Department of Nephrology, The First Affiliated Hospital of Zhejiang Chinese Medical University
Eligibility
Sex/Gender
Male
Age
18 Years to 85 Years
Inclusion criteria
Inclusion criteria: (1) aged 18-85 years old; (2) meet the diagnostic criteria of nephrotic syndrome; (3) renal biopsy showed idiopathic membranous nephropathy.
Exclusion criteria
Exclusion criteria: (1) exclude acute renal failure, renal function stage 3, stage 4 patients; (2) patients with serious primary diseases such as heart, brain, liver or hematopoietic system; (3) excluding lupus, hepatitis b, diabetes and other secondary membranous nephropathy; (4) have a history of mental illness; (5) patients who did not agree to be included in the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| PLA2R;THSD7A;Routine blood;Serum creatinine;Blood urea nitrogen;cholesterol;Serum albumin;TCM syndrome type dialectics;TCM syndrome score;Urine protein quantification for 24 hours; | — |
Secondary
| Measure | Time frame |
|---|---|
| Glutamate transaminase;Glutamate transaminase; | — |
Countries
China
Contacts
Public ContactWen Zhang
Department of Nephrology, The First Affiliated Hospital of Zhejiang Chinese Medical University
Outcome results
None listed