Lung injury
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: (1) Aged 0-18 years; (2) Mechanical ventilation was planned under general anesthesia, and the duration of mechanical ventilation was more than 6 hours; (3) With parents' informed consent and with consent to the follow-up evaluation in accordance with the requirements.
Exclusion criteria
Exclusion criteria: (1) Mechanical ventilation time is less than 6 hours; (2) Severe pulmonary infection existed before surgery; (3) Preoperative pulmonary diseases such as pneumothorax, pulmonary abscess, thoracic deformity, atelectasis and pulmonary arterial hypertension existed; (4) Difficulty in sample collection and incomplete sampling information; (5) The researchers believe that other reasons are not suitable for clinical trials.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| IL-33;Downstream signals of IL-33; | — |
Secondary
| Measure | Time frame |
|---|---|
| Upstream signal of IL-33; | — |
Countries
China
Contacts
Shanghai Children's Medical Center, Shanghai Jiao-Tong University School of Medicine