Skip to content

The effect of dexmedetomidine on multi-mode analgesia on inflammatory response and immune function in patients undergoing thoracoscopic radical resection of lung cancer

The effect of dexmedetomidine on multi-mode analgesia on inflammatory response and immune function in patients undergoing thoracoscopic radical resection of lung cancer

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR1800019796
Enrollment
Unknown
Registered
2018-11-29
Start date
2018-12-01
Completion date
Unknown
Last updated
2018-12-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

lung cancer

Interventions

Group 1:dexmedetomidine whole course pumping
Group 2:The same dose of 0.9% sodium chloride injection was given.

Sponsors

The first affiliated hospital of dalian medical university
Lead Sponsor

Eligibility

Sex/Gender
All
Age
35 Years to No maximum

Inclusion criteria

Inclusion criteria: From December 2018 to June 2019, 60 patients underwent thoracoscopic radical resection of lung cancer in our hospital, American Society of Anesthesiologists (ASA) I-II.

Exclusion criteria

Exclusion criteria: (1) patients who received the chemotherapy, radiotherapy or immunotherapy within two weeks before operation; (2) patients with severe diseases in endocrine or immune system; (3) patients who taking cortisol or angiotensin converting enzyme inhibitors before operation.(4)patients with severe infection, or diseases in respiratory system; (4) patients with severe arrhythmia.

Design outcomes

Primary

MeasureTime frame
Peripheral blood mononuclear NF-kappa B;TNF-a;IL-1;IL-10;CRP;CD4+/CD8+;

Secondary

MeasureTime frame
NRS score after rest and activity;Ramsay;

Countries

China

Contacts

Public ContactQingping Wen

The First Affiliated Hospital of Dalian Medical University

wqp.89@163.com+86 18098877988

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026