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Effect of ?-3 fatty acids on oocyte quality and early embryo development in elderly infertile women

Effect of ?-3 fatty acids on oocyte quality and early embryo development in elderly infertile women

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR1800019772
Enrollment
Unknown
Registered
2018-11-28
Start date
2018-12-01
Completion date
Unknown
Last updated
2018-12-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Infertility

Interventions

DHA group:DHA treatment for 6-8 weeks
ALA group:ALA treatment for 6-8 weeks
Placebo group :Placebo treatment for 6-8 weeks

Sponsors

Center for Reproductive Medicine Affiliated to Shandong University
Lead Sponsor

Eligibility

Sex/Gender
Female

Inclusion criteria

Inclusion criteria: (1) Aged 35-42 years old; (2) undergo cycle of IVF or ICSI; (3) Short-term ovulation induction; (4) omega-3 fatty acid were not taken in the past three months.

Exclusion criteria

Exclusion criteria: (1) Ovarian cyst resection after one-sided ovariectomy in the past; (2) Uterine malformations, such as unilateral uterus, mediastinal uterus, double uterus, double-horned uterus, etc.; (3) Abnormal karyotypes (including polymorphism) of the chromosomes of the husband or herself; (4) suffering from diseases that are not suitable for assisted reproductive technology or for current pregnancy.

Design outcomes

Primary

MeasureTime frame
DHA and ALA level in serum;DHA and ALA level in follicular fluid;Oocyte maturation rate;high quality embryo rate;—

Secondary

MeasureTime frame
height;weight;waistline;hipline;—

Countries

China

Contacts

Public ContactLing Geng

Center for Reproductive Medicine Affiliated to Shandong University

gengling@sduivf.com+86 0531-85651391

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026