Major Depressive Disorders
Conditions
Interventions
Gold Standard:The Hamilton Depression Rating Scale
cognition 
based 
psychological 
assessment 
Sponsors
Beijing Anding Hospital of Capital Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1) Outpatient patients aged 18 to 65 years old male and female; 2) Meet the diagnostic criteria for major depressive disorder in the 5th edition of the American Diagnostic and Statistical Manual of Mental Diseases (DSM-5); 3) Screening and baseline 17 Hamilton Depression Scale (HAMD-17) scores =7; 4) No antidepressants were taken in 2 weeks (no fluoxetine was taken in 4 weeks); 5) Normal vision or correction (1.0); 6) Understanding and voluntarily participating in this study, signed the informed consent.
Exclusion criteria
Exclusion criteria: 1) Comorbid with other mental disorders diagnosed by DSM-5 or psychotic symptoms; 2) At present, patients have severe suicide risk, or HAMD-17 item 3 suicide score = 3; 3) Alcohol or drug abuse or dependence within 6 months before screening; 4) Comorbid with severe or unstable physical diseases, including any cardiovascular, tumors, kidneys, respiratory, endocrine (including thyroid dysfunction), digestion, blood (such as those with bleeding tendency) or nervous system diseases; 5) With history of epilepsy, except convulsions caused by febrile convulsions in children; 6) Patients with eye diseases; 7) Screening patients who underwent electroconvulsive therapy, transcranial magnetic stimulation therapy and phototherapy in the first three months. (8) Women in breastfeeding, pregnancy or those who have fertility requirements during the trial (including men), as well as male and female patients who are unable to undergo safe and effective contraceptive treatment with antidepressants; 9) color blindness or color weakness; 10) Researchers do not consider patients suitable for other conditions in the group.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Correlation between Image cognition based psychological status assessment and HAMD-17; | — |
Secondary
| Measure | Time frame |
|---|---|
| Correlation between Image cognition based psychological status assessment and each dimensions of clinician/self rate scales at baseline assessment;Correlation between Image cognition based psychological status assessment and the severity of clinician/self rate scales at baseline assessment;The stability of Image cognition based psychological status assessment during follow up;The agreement between Image cognition based psychological status assessment and symptoms severity at follow up;The predictiveness of Image cognition based psychological status assessment for severity at follow up;Difference of Image cognition based psychological status assessment index between different comorbidity subgroup (anxiety/non-anxiety, somatic symptoms/no somatic symptoms); | — |
Countries
China
Contacts
Public ContactYuan Feng
Beijing Anding Hospital of Capital Medical University
Outcome results
None listed