Effect of goal-directed fluid therapy on hemodynamics and neonatal outcomes in cesarean section - a single-center, randomized, parallel-controlled, superiority clinical trial

Status

Recruiting

Phases

Phase 4

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR1800019752

Enrollment

Unknown

Registered

2018-11-26

Start date

2018-11-27

Completion date

Unknown

Last updated

2020-07-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hypotension

Interventions

GDFT group:Target-directed fluid therapy before delivery

control group:Fluid infusion at a rate of 2ml/kg/h

Eligibility

Sex/Gender

Female

Inclusion criteria

Inclusion criteria: 1. Pregnancy = 37 weeks, singleton; 2. ASA=2; 3. Planned elective cesarean section.

Exclusion criteria

Exclusion criteria: 1. Have hypertension, severe arrhythmia and other cardiovascular diseases; 2. Intraspinal anesthesia contraindications; 3. It is known that the fetus has congenital deficiency such as intrauterine hypoxia or deformity; 4. Preoperative evaluation of bleeding may be more than 400ml (such as placenta).

Design outcomes

Primary

Measure	Time frame
The incidence of hypotension before delivery;	—

Secondary

Measure	Time frame
Vasoactive drug dosage before delivery;Incidence of nausea and vomiting before delivery;Incidence of fetal acidosis;Incidence of neonatal adverse events;	—

Countries

China

Contacts

Public ContactYuantao Li

Shenzhen Maternity and Child Healthcare Hospital

sylyt6788@sina.com+86 15013857589

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026