Cardiac injury after CPB
Conditions
Interventions
Group 1:infusion of saline
Group 2:infusion of Xuebijing
Sponsors
Second Affiliated Hospital of Harbin Medical University
Eligibility
Sex/Gender
Male
Age
25 Years to 65 Years
Inclusion criteria
Inclusion criteria: 60 patients with CPB, ASA II-III, heart function II-III, aged 25 to 65 years old.
Exclusion criteria
Exclusion criteria: 1. A diagnosis of acute myocardial infarction within the last 4 weeks prior to the scheduled surgery; 2. an activated phase of rheumatic diseases; 3. left ventricular ejection frac?tion of <40%; 4. preoperatively confirmed intra cardiac shunt; 5. a hematocrit of <30%; 6. severe systemic diseases, including pulmonary diseases, hepatic, renal, musculoskeletal diseases or immune system illnesses. Additionally, patients receiving oral hypoglycemic agents or theophyllines were excluded since these medications are known to influence the process of ischemia reperfusion injury.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| TnI; | — |
Secondary
| Measure | Time frame |
|---|---|
| CK-MK;Ejection fraction;TNF;IL-1;IL-8;IL-10;MCP-1;IFN;stay in ICU;time of discharge;CVP;MAP;CI; | — |
Countries
China
Contacts
Public ContactWei Gao
Department of Anesthesiology, the Second Affiliated Hospital of Harbin Medical University
Outcome results
None listed