Facial rejuvenation
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Healthy women aged 35 to 50 WSRS(wrinkle severity rating scale) =2; 2. According to Fitzpatrick classification, skin classification is type III - IV; 3. Able to read and understand all contents of the informed consent form, sign the informed consent form voluntarily and complete the entire research steps as required by the program; 4. Facial skin is basically complete, without ulceration, exudation, etc.; 5. No invasive treatment, laser photon cosmetology or similar treatments were used on the face 3 months before treatment; 6. Oral administration of hormone drugs, collagen, hyaluronic acid and other cosmetic drugs and health care products was not systematic 3 months before treatment; 7. After participating in this experiment, there was no significant change in lifestyle, including diet and skin care; 8. Do not use any cosmetics, drugs or health care products that may affect the results during the test period; 9. Can maintain the regularity of life during the study, avoid sunlight ultraviolet ray irradiation.
Exclusion criteria
Exclusion criteria: 1. Women who are pregnant or breast-feeding; 2. Acute allergy period or allergic to test and control products; 3. Patients with active skin diseases (such as eczema, acne, psoriasis, etc.) or with obvious redness and swelling near the test area, tattoo; 4. Has received or is receiving medication or physical therapy for any skin disease or systemic disease within the last 3 months; 5. Oral or external use of beauty products that may have an impact on the test results within 2 weeks; 6. Patients with serious primary diseases and mental diseases such as serious cardiovascular and cerebrovascular diseases, liver and kidney diseases and hematopoietic diseases; 7. Participating in other clinical trials;The researchers considered it inappropriate to participate in the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| skin pores;UV spots;black brown spots;Erythema;skin transepidermal water loss;skin melanin index; skin erythema index;symptoms index;Therapeutic index; | — |
Secondary
| Measure | Time frame |
|---|---|
| skin texture;skin winkle; | — |
Countries
China
Contacts
Department of Dermatology, Beijing Friendship Hospital, Capital Medical University