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Effect of three day antagonist pretreatment before superovulation initiation on outcome of in vitro fertilization-embryo transfer treatment with antagonist protocol: a randomized controlled trial

Effect of three day antagonist pretreatment before superovulation initiation on outcome of in vitro fertilization-embryo transfer treatment with antagonist protocol: a randomized controlled trial

Status
Recruiting
Phases
Phase 4
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR1800019730
Enrollment
Unknown
Registered
2018-11-26
Start date
2018-12-01
Completion date
Unknown
Last updated
2023-06-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

infertility

Interventions

experimental group:GnRH-ant pretreatment was used on the 2nd to 4th day of menstruation

Sponsors

The People's Hospital of Guangxi Zhuang Autonomous Region
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
20 Years to 39 Years

Inclusion criteria

Inclusion criteria: 1. Female aged less than 40 years old; 2. Regular menstrual cycle (21-35 days), bilateral ovaries exist, vaginal b-mode ovaries are clearly displayed, and there is no hormonal therapy for nearly a month; 3. The endometrium is normal and has no history of hysterectomy.

Exclusion criteria

Exclusion criteria: 1. Menstrual disorders, abnormal endocrine hormones, such as hyperprolactinemia, thyroid diseases; 2. History of uterine and ovarian surgery; 3. Ovarian reserve function decreased, FSH>12U/L or AFC 30kg /m2; 6. Male severe oligospermia or obstructive azoospermia; 7. Patients with known congenital adrenal hyperplasia.

Design outcomes

Primary

MeasureTime frame
Oocyte number;

Secondary

MeasureTime frame
Gn dose;Gn days;Number of mature eggs;Fertilization rate;Good embryo number;Implantation rate;clinical pregnancy rate;ongoing pregnancy rate;rate of abortion;live birth rate;

Countries

China

Contacts

Public ContactZhang Yisheng

The People's Hospital of Guangxi Zhuang Autonomous Region

175125941@qq.com+86 151 7717 2501

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 21, 2026