postoperative nausea and vomiting
Conditions
Interventions
Group O:4mg ondansetron
Group OD:4mg ondansetron+8mg dexamethasone
Group ODH:4mg ondansetron+8mg dexamethasone+2mg haloperidol
Sponsors
Second Hospital of Tianjin Medical University
Eligibility
Sex/Gender
Female
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: Recruited subjects were eligible consecutive female smoking patients ranked as American Society of Anesthesiologists (ASA) physical status I-II and aged between 18-60 years, who were scheduled for laparoscopic myomectomy and laparoscopic adnexectomy. Active smoking was defined as having smoked at least one cigarette per day in the week prior to surgery.
Exclusion criteria
Exclusion criteria: Known allergy or intolerance to the study drug; vomiting within the 24 h before surgery; a history of PONV or motion sickness; body mass index (BMI) =35 or =18.5; gastrointestinal, renal or hepatic disease; cardiac arrhythmia; insulin-dependent diabetes; psychiatric illness; use of opioids or corticosteroids within 1 week of surgery; use of anti-emetics in the 24 h prior to surgery; currently pregnant or lactating; and requiring a >3 h operation or anesthesia time and/or preservation of the gastric tube following operation.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Postoperative Nausea;Postoperative Vomoting;Postoperative rescue antiemetic usage; | — |
Secondary
| Measure | Time frame |
|---|---|
| Postoperative VAS score;Postoperative analgesics usage; | — |
Countries
China
Contacts
Public ContactZhuang Xinqi
Second Hospital of Tianjin Medical University
Outcome results
None listed