Severe hepatitis
Conditions
Interventions
Group 1:Plasma not be exchange
Group 2:Fresh frozen plasma plasma exchange
Group 3:Frozen plasma plasma exchange
Group 4:Virus inactivates frozen plasma exchange
Group 5:Mixed plasma exchange
Sponsors
The First Affiliated Hospital of Nanchang University
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Aged at least 18 years; 2. Confirmed severe hepatitis; 3. Patients with informed consent and signature of informed consent;
Exclusion criteria
Exclusion criteria: 1. Pregnant or lactating women; 2. High variability of clinical outcomes due to cases transferred to other medical institutions after treatment but not recorded or controlled by other medical institutions; 3. Coagulation factor deficiency disease, thrombocytopenia; 4. History of severe heart, lung, liver, kidney, tumor and other important organ diseases; 5. Lung infection, urinary tract infection, wound infection at admission; 6. May die within 1 hour after admission; 7. Burn surface area = 20% or suspicious inhalation injury; 8. Participated in other clinical studies.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| effective rate;in-hospital mortality;30 d mortality; | — |
Secondary
| Measure | Time frame |
|---|---|
| complications;length of stay;ICU length of stay; | — |
Countries
China
Contacts
Public ContactLe Aiping
The First Affiliated Hospital of Nanchang University
Outcome results
None listed