major burn
Conditions
Interventions
massive plasma transfusion group:plasma transfuion =2000mL
non-plasma transfuion group:plasma transfuion < 2000mL
non-transfusion group:No plasma transfusion
Sponsors
The First Affiliated Hospital of Nanchang University
Eligibility
Sex/Gender
Male
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: (1) Aged at least 18 years old; (2) admitted to the hospital within 4 hours after the burn; (3) The burn area is =30%; (4) Patients who gave informed consent and signed informed consent.
Exclusion criteria
Exclusion criteria: (1) pregnant or lactating women; (2) Transferred by other medical institutions after treatment, but the case data provided by other medical institutions cannot record or control the quality, resulting in high variability of clinical results; (3) coagulation factor deficiency, thrombocytopenia; (4) a history of serious organ diseases such as heart, lung, liver, kidney and tumor; (5) Pulmonary infection, urinary tract infection, and wound infection have occurred at the time of admission; (6) may die within 1 hour after admission; (7) Participated in other clinical studies.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 24 h mortality;in-hospital mortality;30 d mortality; | — |
Secondary
| Measure | Time frame |
|---|---|
| complications;length of stay;ICU length of stay; | — |
Countries
China
Contacts
Public ContactLe Aiping
The First Affiliated Hospital of Nanchang University
Outcome results
None listed