functional constipation
Conditions
Interventions
herbs powder and diet group:herbs powder 15g bid and diet intervation
forlax and diet group:forlax 10g bid and diet intervation
forlax group:forlax 10g bid
forlax placebo and diet group:forlax placebo 10g bid and diet intervation
forlax placebo group:forlax placebo 10g bid
herbs powder group:herbs powder 15g bid
herbs powder placebo and diet group:herbs powder placebo 15g bid and diet intervation
herbs powder group:herbs powder placebo 15g bid
Sponsors
China-Japan Friendship Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: (1) Aged 18-75 years old; (2) meet the diagnostic criteria of Rome IV; (3) The characters of stool are Bristol1, 2, 3 (typical constipation) and 4, 5, 6 (non-typical constipation); (4) patient who is according to TCM diagnosis of gastrointestinal dampness and heat; (5) sign informed consent.
Exclusion criteria
Exclusion criteria: (1) a woman who is pregnant, preparing for pregnancy or lactation; (2) patient who has serious heart,brain and kidney diseases and in the situation of generally poor or organ failure; (3) patient who has diabetes,hypothyroidism and long-term use of drugs affecting constipation; (4) Gastrointestinal organic diseases, such as intestinal tuberculosis, intestinal obstruction, intestinal cancer, etc.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Complete voluntary defecation frequency per week; | — |
Secondary
| Measure | Time frame |
|---|---|
| gastrointestinal transit time;high resolution anorectal manometry;faecal flora determination;constipation-related symptom rating scale;Traditional Chinese Medicine syndrome score scale; | — |
Countries
China
Contacts
Public ContactShukun Yao
China-Japan Friendship Hospital
Outcome results
None listed