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PAI-1 4G/5G polymorphism and risks of peripherally inserted central catheter-related upper extremity venous thrombosis in cancer patients

Study on precise prevention strategy of PICC-related thrombus in patients with malignant tumor

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR1800019681
Enrollment
Unknown
Registered
2018-11-22
Start date
2018-12-01
Completion date
Unknown
Last updated
2018-11-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cancer

Interventions

Experimental group :The high-risk genotype will be given low molecular weight heparin sodium 0.4ml through subcutaneous injection once daily for 5 days, combined with physical prevention (heat compre
the low-risk genotype would only be given heat protection.
Control group:heat compress 30 minutes a time, 2 times a day for 1 week

Sponsors

West China Hospital, Sichuan University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: Eligible patients were adult lung cancer patients who are going to have a catheterization of PICC, whose life expectancy was over 3 months and no significant abnormal organ function.

Exclusion criteria

Exclusion criteria: Venous thrombus formed before PICC placement, recent use of anticoagulants, pregnant, lactating women and patients who were in process of other clinical trials.

Design outcomes

Primary

MeasureTime frame
PAI-1 genotype;Incidence rate of PICC-UEVT;—

Secondary

MeasureTime frame
Incidence time of PICC-UEVT;—

Countries

China

Contacts

Public ContactLi Junying

West China Hospital, Sichuan University

lijunying2005@sina.com+86 18980601764

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026