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A cohort study for embryo-fetal origin of diseases among offsprings conceived by assisted reproductive technology

Study for adverse effect of high maternal estradiol environment induced by controlled ovarian hyperstimulation on outcomes of frozen-thawed embryo transfer

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR1800019659
Enrollment
Unknown
Registered
2018-11-21
Start date
2014-01-01
Completion date
Unknown
Last updated
2018-11-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

embryo-fetal origin of diseases

Interventions

Case series:Maternal estradiol level induced by controlled ovarian hyperstimulation

Sponsors

International Peace Maternity and Child Health Hospital affiliated to Shanghai Jiao Tong University, School of Medicine
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
20 Years to 40 Years

Inclusion criteria

Inclusion criteria: 1. Plan to pregnancy after in vitro fertilization and embryo transfer in International Peace Maternity and Child Health 2. Hospital affiliated to Shanghai Jiao Tong University, School of Medicine; 3. Retrieving occytes induced by controlled ovarian hyperstimulation; 4. Undergoing frozen-thawed embryo transfer; 5. Able to read, understand and sign the consent form.

Exclusion criteria

Exclusion criteria: 1. Woman older than 40 years; 2. Foreigners; 3. Undergoing mixed transfer cycles; 4. Undergoing preimplantation genetic diagnosis or preimplantation screening; 5. Receiving donated oocytes or sperm.

Design outcomes

Primary

MeasureTime frame
maternal serum estradiol;—

Secondary

MeasureTime frame
maternal serum estradiol;maternal serum luteinizing hormone;maternal serum progesterone;number of occytes retrieved;number of embryo transferred;duration of embryo cryopreservation;maternal endomertrial thickness;maternal age;maternal BMI;birthweight of neonate;gestational age;—

Countries

China

Contacts

Public ContactHefeng Huang

International Peace Maternity and Child Health Hospital affiliated to Shanghai Jiao Tong University, School of Medicine

huanghefg@126.com+86 021 64073897

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026