Neuromuscular transmission of the foot
Conditions
Interventions
Foot (stimulation: posterior tibial nerve, measurement: short flexor hallucis):7/5000 Cìji jìng hòu shénjing Stimulating posterior tibial nerve
Hand (stimulation: ulnar nerve, measurement: thumb adductor):Stimulating ulnar nerve
Sponsors
The Third Affiliated Hospital of Sun Yat-sen University
Eligibility
Sex/Gender
All
Age
3 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. Patients agrees and signs an informed consent form; 2. Patients should undergo general anesthesia surgery and use muscle relaxants. The limbs are exposed and fixed in vitro, the skin is intact, and there is no inflammation or obvious damage; 3. ASAI ~ III, no serious heart, lung, liver, kidney dysfunction;. 4. Aged 3 to 65 years old, BMI 16 ~ 28kg / m2, regardless of gender; 5. Previously no myasthenia gravis affects diseases such as muscle nerve junction transmission.
Exclusion criteria
Exclusion criteria: 1. nerve injury or other neuromuscular diseases, preoperative application of drugs that affect neuromuscular conduction and patients with severe liver and kidney disease; 2. patients with inflammation or obvious damage to the skin of the ulnar and sacral nerves; 3. a patient wearing an implantable cardiac pacemaker; 4. Body mass index > 28kg/m2; 5. Coronary heart disease and neostigmine contraindications; 6. need to retain the tracheal catheter after surgery to return to the intensive care unit to continue treatment; 7. Patients considered by other clinicians to be unsuitable for clinical trials
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| TOFR; | — |
Countries
China
Contacts
Public ContactLi Shangrong
The Third Affiliated Hospital of Zhongshan University
Outcome results
None listed