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Effect of acupuncture on esophageal motility: A study using high-resolution manometry in refractory gastroesophageal reflux disease

Effect of acupuncture on esophageal motility: A study using high-resolution manometry in refractory gastroesophageal reflux disease

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR1800019646
Enrollment
Unknown
Registered
2018-11-02
Start date
2014-08-01
Completion date
Unknown
Last updated
2018-11-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Refractory Gastroesophageal Reflux Disease

Interventions

Group 2:dorsal position

Sponsors

Shanghai Jiaotong University School of Medicine Affiliated Ruijin hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 70 Years

Inclusion criteria

Inclusion criteria: 1. gastroesophageal reflux disease-related symptoms, such as: heartburn, pantothenic acid, burning after sternum, supine or coughing during sleep, throat discomfort, GERD Q score = 8 points; 2. Gastroesophageal reflux disease was clearly confirmed by gastroscopy or 24-hour esophageal PH monitoring Confirmed acid reflux; 3. Failure of standard dose proton pump inhibitor therapy for 8 weeks or more after continuous administration; 4. conscious and able to express subjective symptoms.

Exclusion criteria

Exclusion criteria: 1) Incorporating one of the following diseases of the digestive system: peptic ulcer, history of gastroesophageal or duodenal surgery, zollinger-ellison syndrome, primary esophageal motility disorders (eg, achalasia, scleroderma) , primary esophageal fistula), upper gastrointestinal malignancy, drug esophagitis, nasopharyngeal or esophageal obstruction; 2) long-term use of other drugs for the treatment of gastroesophageal reflux disease, and did not disable one month before the study; 3) severe mental illness, or other understanding of the treatment of disorders can not meet the patient on time and related examination; 4) severe heart, lung, cerebrovascular diseases and hematopoietic diseases, or coagulation dysfunction; 5) Currently during pregnancy and lactation; 6) skin lesions, skin infections and other acupuncture taboos.

Design outcomes

Primary

MeasureTime frame
normal contraction;intact contraction;

Secondary

MeasureTime frame
distal contractile integral;integrated relaxation pressure;distal latency;large break in the 20mmhg isobaric contour;mean basal LES pressure;the length of LES;mean basal UES pressure;UES relaxation pressure;

Countries

China

Contacts

Public ContactYao Weiyan

Shanghai Jiaotong University School of Medicine Affiliated Ruijin Hospital

ywy11419@rjh.com.cn+86 13917519286

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 9, 2026