knee osteoarthritis
Conditions
Interventions
Group 1:high moxibustion dose
Group 2:Low moxibustion dose
Sponsors
Hebei University of Chinese Medicine
Eligibility
Sex/Gender
All
Age
45 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. Meeting the knee osteoarthritis criteria; 2. Aged 45–75 years; 3. Unilateral or bilateral knees pain ,duration of more than 6 months; 4. Radiological assessment of knee osteoarthritis rated as grade 1,2 and 3 on the Kellgren-Lawrence Grading Scale in previous 6 months; 5. An overall score is from 4 to 7 on the Number Rating Scale(NRS); 6. Signing informed consent.
Exclusion criteria
Exclusion criteria: 1. Surgery history in the target knee joint or waiting for knee surgery(?total?knee?arthroplasty or arthroscopy); 2. Knee pain caused by other diseases(joint free body, severe effusion in the joint cavity,infection,malignant tumor,autoimmune disease,trauma,fracture,gout,and so on ); 3. Arthroscopy history in the target knee joint in previous 1 year and intra-articular injection history in the target knee joint in previous 4 months; 4. History of moxibustion treatment in previous 3 months; 5. Any serious organic or mental diseases; 6. Coagulation disorder 7. With Cardiac pacemaker; 8. Pregnant and intentional pregnancy or lactation women; 9. Participating in other clinical trials; 10. Refusal to sign informed consent.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| NRS;WOMAC; | — |
Secondary
| Measure | Time frame |
|---|---|
| SF-12;NRS;Pain sub-table in WOMAC;Functional sub-table in WOMAC;Stiff sub-table in WOMAC;Overall Treatment Efficacy;Body surface temperature;Blood pressure;Electrocardiogram;Blood routine examination;urine routine examination;Liver function test;Renal function test;Tumor Necrosis Factor-a;Interleukin-10;Superoxide Dismutase; | — |
Contacts
Public ContactChunsheng Jia
Hebei University of Chinese Medicine
Outcome results
None listed