Retrobulbar dexmedetomidine in Pediatric Vitreoretinal Surgery Eliminates the Need for Intraoperative Fentanyl and Postoperative Analgesia,A Randomized Controlled Study

Effects of retrobulbar dexmedetomidine with local anesthesia in vitreoretinal surgery

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR1800019634

Enrollment

Unknown

Registered

2018-11-20

Start date

2018-11-26

Completion date

Unknown

Last updated

2018-11-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

vitreoretinal surgery

Interventions

RD group:general anesthesia plus retrobulbar dexmedetomidine

RB group:general anesthesia plus retrobulbar block

F group:general anesthesia alone

Eligibility

Sex/Gender

All

Age

2 Years to 7 Years

Inclusion criteria

Inclusion criteria: Consecutive children with American Society of Anesthesiologists physical status I to II, aged 2 to 7 years, who underwent elective vitreoretinalsurgery

Exclusion criteria

Exclusion criteria: parent unwillingness to give consent; a history of upper airway infection less than 4 weeks before the surgery; allergy to local anesthetics, dexmedetomidine, and opioids; presence of eye tumors or infections; or blindness in the eye not being operated on.

Design outcomes

Primary

Measure	Time frame
consumption of fentanyl;	—

Secondary

Measure	Time frame
stress response;Pain score;	—

Countries

China

Contacts

Public ContactWeidi Ye

The Second Affiliated Hospital, Zhejiang University School of Medicine

ywdyjj@126.com+86 13958092082

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026