Cervical esophageal cancer
Conditions
Interventions
Case series:Planned surgery after concurrent chemoradiotherapy.
Sponsors
Shandong ENT Hospital Affiliated to Shandong University
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. Cervical esophageal squamous cell carcinoma confirmed by pathology; 2. The lesion is suitable for concurrent chemoradiotherapy and potentially resectable; 3. The patients could provide biopsy,fresh tumor tissue or pleuroperitoneal fluids samples; 4. Without distant metastasis; 5. Without making radical head and neck surgery; 6. Life expectancy = 6 months, age 18-75 years old and ECOG 0-1; 7. Without obvious abnormalities of ECG; 8. Without obvious abnormalities of blood routine, liver function and renal function affectting concurrent chemoradiotherapy and surgery; 9. Have not received any chemotherapy and radiation therapy and endocrine therapy; 10. The patient voluntarily signed the informed consent form, with good compliance, willing active treatment and follow-up.
Exclusion criteria
Exclusion criteria: 1. Planned surgery cannot be performed after radiotherapy and chemotherapy; 2. The patient was confirmed to living with other cancers which may cause interferences to this resaerch; 3. Cannot quit tobacco and alcohol during treatment; 4. Pregnant and lactating women; 5. With active gastrointestinal bleeding; 6. Combined with other serious diseases, such as myocardial infarction within 6 months, malignant hypertension, chronic pancreatitis, hepatitis B antigen positive, etc; 7. Participate in other clinical trials within or four weeks.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| PFS;OS;Local control rate; | — |
Countries
China
Contacts
Public ContactWei Xu
Shandong ENT Hospital Affiliated to Shandong University
Outcome results
None listed