gout
Conditions
Interventions
Group 1:Ozone treatment of autologous blood
Group 2:Etoricoxib
Group 3:Ozone treatment of autologous blood and etoricoxib
Sponsors
Sir Run Run Hospital, Nanjing Medical University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Gout were established according to the diagnostic criteria for gout in the American College of Rheumatology; 2. Aged 18-60 years old; 3. The numerical rating scale (NRS) score of the joint is = 4 points.
Exclusion criteria
Exclusion criteria: 1. Systemic application of glucocorticoids, other immunosuppressive drugs or biological immunomodulators, antibiotics, probiotics and other microecological preparations within 6 months prior to enrollment; 2. Active infection (including human immunodeficiency virus (HIV), hepatitis B and hepatitis C virus infection or tuberculin test positive); 3. The affected joint also has rheumatoid arthritis, infectious arthritis or other arthritis; 4. Severe liver and kidney disease, history of peptic ulcer or bleeding, history of heart, cerebrovascular disease and blood system diseases; 5. Hyperthyroidism; 6. Havism; 7. Contraindications for NSAIDs; 8. Intra-articular hormone injection therapy in the past 4 weeks; 9. Pregnant or lactating woman; 10. Patients who are participating in other clinical trials; 11. Patients who suffer from mental illness, patients who are unwilling to receive ozonated autohemotherapy and researchers judged that the patients unsuitable for clinical trials.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| uric acid;symptom; | — |
Secondary
| Measure | Time frame |
|---|---|
| blood lipid;blood glucose;BMI;Liver function;Kidney function;HbA1c; | — |
Countries
China
Contacts
Public ContactLiu Yu
Sir Run Run Hospital, Nanjing Medical University
Outcome results
None listed