A study of efficacy of dexmedetomidine with butorphanol for analgesia and sedation in neurosurgical patients

Status

Recruiting

Phases

Phase 4

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR1800019592

Enrollment

Unknown

Registered

2018-11-19

Start date

2018-10-01

Completion date

Unknown

Last updated

2018-11-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

hematencephalon?craniocerebral injury

Interventions

Treatment group:Intravenous dexmedetomidine

control group:with a placebo saline solution

Eligibility

Sex/Gender

All

Age

18 Years to 75 Years

Inclusion criteria

Inclusion criteria: 1. Patients admitted to neurosurgery ICU (patients with brain injury and cerebral hemorrhage); 2. Aged 18-70 years old; 3. weight 40-100 kg.

Exclusion criteria

Exclusion criteria: 1. Pregnancy and lactation; 2. Participated in other clinical research patients within three months; 3. Patients with severe hepatic and renal insufficiency.

Design outcomes

Secondary

Measure	Time frame
Hemodynamic changes;Glasgow Coma Scale;adverse effect;	—

Primary

Measure	Time frame
Critical care Pain Observation Tool;Richmond Agitation-Sedation Scale;	—

Countries

China

Contacts

Public ContactJincao Chen

Zhongnan Hospital of Wuhan University

1577380440@qq.com+86 13678487989

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026