Iatrogenic ulcer after ESD treatment
Conditions
Interventions
Group 1:PPI treatment only after gastric ESD
Group 2:PPI+sucralfate treatment after gastric ESD
Sponsors
the First People's Hospital of Yunnan Province
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Patients will be indicated for gastric ESD if they have either benign or malignant gastric mucosal or submucosal lesions such as early gastric cancer, stromal tumor, lipoma, comlying with documented indication of gastric ESD. Patients inlucded should have a test for H.pylori infection. Positive H.pylori infection are defined by C-urea breath tests.
Exclusion criteria
Exclusion criteria: 1. are = 20 yrs; 2. have diabetes, cirrhosis with abnormal coagulation, hematological disorders with coagulation abnormality, and autoimmune diseases that may delay ulcer healing; 3. have to use drugs such as antithrombotic drugs (asprin, clopidogrel, heparin, e.g.), NSAIDs, glucocorticoid pre- and post-ESD; 4. have a history of allergy to the test drugs; 5. have a history of gastrectomy; 6. are of pregnancy or lactation.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| transfer rate to the ulcer at scar stage; | — |
Secondary
| Measure | Time frame |
|---|---|
| scarring rate of the ulcer; | — |
Countries
China
Contacts
Public ContactQiang Guo
Department of Gastroenterology, the First People's Hospital of Yunnan Province
Outcome results
None listed