Male erectile dysfunction
Conditions
Interventions
Group 1:Single injection of autologous fat extracting tissue of the corpus cavernosum
Group 2:Take tadalafil 5mg once a night for 14 consecutive days
Sponsors
Urology & Andrology Renji Hospital, Shanghai Jiaotong University School of Medicine
Eligibility
Sex/Gender
Male
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1. Aged 18 to 70 years old, moderate and severe male penile erectile dysfunction, international erectile function score questionnaire - EF (IIEF-EF) score of 6-16 points; 2. Phosphodiesterase inhibitors are ineffective or ineffective; 3. The external genitalia develops normally, and there is no obvious abnormality in bilateral testicular, epididymis and spermatic cord palpation; 4. Willing to limit alcohol intake and stop taking drugs that affect sexual function (such as androgen replacement drugs, phosphodiesterase inhibitors and some proprietary Chinese medicines); 5. No life-threatening cardiovascular or endocrine diseases; 6. Volunteer to participate in the experiment and agree to follow-up.
Exclusion criteria
Exclusion criteria: 1. Other diseases in crisis other than erectile dysfunction, such as severe cardiovascular disease (such as angina pectoris, myocardial infarction, heart failure and arrhythmia), renal failure, respiratory failure, etc. 2. Androgen levels below 200 ng/dl; 3. After the researcher judges, has a history of obvious penile malformation, or has been treated with penile prosthesis implantation; 4. The patient's sexual partner plans to become pregnant during the study; 5. Currently participating, or have withdrawn from another clinical study that is incompatible with this study within the past 30 days; 6. Failure to adhere to hospital visits and follow-up, or other treatments during follow-up.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| IIEF-EF; | — |
Secondary
| Measure | Time frame |
|---|---|
| EHS;NPT;Penile Doppler ultrasound;Penis length without erection;testosterone;PSA; | — |
Countries
China
Contacts
Public ContactLu Mujun
Renji Hospital, Shanghai Jiaotong University School of Medicine
Outcome results
None listed