Gastric cancer
Conditions
Interventions
Case series:MINIPDX susceptibility testing for personalized therapy
Sponsors
Wuxi Hospital of Traditional Chinese Medicine
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Histopathological examination of patients with advanced or recurrent gastric cancer; 2. The time post-chemotherapy is = 4 weeks; 3. The damage caused by other treatment has been restored; 4. No other neoplastic diseases based on clinical diagnosis; the main organs (liver, kidney, heart) are healthy; 5. The patients could provide biopsy or fresh tumor tissue samples; 6. Objective tumors that meet RECIST 1.1 criteria and can be evaluated by CT/MRI; 7. KPS score = 60, expected survival time = 3 months; Comprehensive assessment of patients who can tolerate chemotherapy and targeted therapy; 8. Subjects volunteered to participate, signed informed consent, good compliance, active treatment and follow-up;
Exclusion criteria
Exclusion criteria: 1. The patients were in poor condition without tolerance of surgery or post-surgery chemtherapy; 2. Combined metastasis; unstable angina, symptomatic congestive heart failure, severe arrhythmia, myocardial infarction in the past 6 months, prolonged QT interval (>450ms); 3. Other malignant tumor occurred within the past 5 years; 4. The patient cannot be followed up or is participating in other clinical trials; 5. There is drug abuse; or any medical, psychological or social condition that may affect the study, patient compliance, or even compromise the safety of the patient; 6. Perform other experimental drug treatments other than this test within 4 weeks before the start of the study; or participate in another clinical study that has an impact on the results of this study; 7. Mental or medical instability makes the patient unable or unwilling to sign an informed consent form; 8. The patients were considered unsuitable for participating in the study by the investigators based on comprehensive assessments.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Objective response rate;Progress-free survival; | — |
Secondary
| Measure | Time frame |
|---|---|
| Overall survival;Five-year survival rate;Quality of life score; | — |
Countries
China
Contacts
Public ContactChunhui Jin
Wuxi Hospital of Traditional Chinese Medicine
Outcome results
None listed