Infertility
Conditions
Interventions
Group 1:Tadalafil supplementation in cycle regimens to prepare the womb lining for ovulation induction cycle FET
Group 2:ovulation induction cycle FET
Sponsors
Shanghai Orient Hospital,Tongji University School of Medicine
Eligibility
Sex/Gender
Female
Age
20 Years to 40 Years
Inclusion criteria
Inclusion criteria: 1. Women aged 20–40 years old, body mass index 18-30 kg/m2; 2. Women who have experienced repeated implantation failure(RIF)while transplant high quality embryos=2 times, planned to perform FET again; 3. Women who have more than 2 high-quality embryos.
Exclusion criteria
Exclusion criteria: 1. with significant systemic diseases not suitable for pregnancy, (including hyperthyroidism, diabetes, lupus erythematosus); 2. space-occupying lesions in uterine cavity, severe intrauterine adhesions ( IUAs); 3. uterine malformationl; 4. cervical incompetence; 5. adenomyosis; 6. abnormal karyotype; 7. recurrent spontaneous abortions; 8. reproductive tract tumors; 9. acute or chronic inflammation of reproductive tract.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Clinical pregnancy rate; | — |
Secondary
| Measure | Time frame |
|---|---|
| Embryo implantation rate;Biochemical pregnancy rate;Cumulative live birth rate;Early abortion rate; | — |
Countries
China
Contacts
Public ContactQian Ying
Shanghai Orient Hospital, Tongji University School of Medicine
Outcome results
None listed