acute respiratory distress syndrome
Conditions
Interventions
Control group:ARDS conventional therapy
Sponsors
Children's Hospital of Shanghai
Eligibility
Sex/Gender
All
Age
1 Years to 18 Years
Inclusion criteria
Inclusion criteria: (1) Aged from 1 month to 18 years old; (2) Be diagnosed with severe ARDS according to the Berlin definition of acute respiratory distress syndrome and "2015 Consensus Recommendations from the Pediatric Acute Lung injury Consensus Conference"; (3) Signed informed consent by patients or their guardians.
Exclusion criteria
Exclusion criteria: (1) Patients who are already have chronic lung disease; (2) Be out of 7 days after diagnosed with ARDS; (3) Advanced neoplasm and leukemia complication with ARDS; (4) Be hypersusceptibility or intolerance to bio-membrane; (5) With severe disease of heart, liver, renal and hematological system; (6) Participate in other clinical trials in last 3 months; (7) Any medical history that can disturb the clinical results and increase risk of patients; (8) Patients' compliance is not very well and can't complete the trial strictly.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 28 days survival rate; | — |
Secondary
| Measure | Time frame |
|---|---|
| Pulmonary mechanics index (Cydn, Pao2/Fio2, EVLWI, PIVI);Indexes of heart function (CO, GEDI, CI, GEF, PVR, dPmx); | — |
Countries
China
Contacts
Public ContactCui Yun
Children's Hospital of Shanghai
Outcome results
None listed